Funding Opportunities

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Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R21)

National Institute of Health
http://grants1.nih.gov/grants/guide/pa-files/PA-10-128.html#PartI

This Funding Opportunity Announcement (FOA) issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Heart, Lung and Blood Institute (NHLBI), and the Office of Behavioral and Social Science Research (OBSSR), National Institutes of Health, invites Research Project Grant (R01) applications from institutions/organizations that propose randomized clinical trials testing novel home- or family-based interventions for the prevention or management of overweight in infancy and early childhood. Tested interventions can use behavioral (including dietary and physical activity), environmental, or other relevant approaches. Applications should focus on infants and young children (to age six years) and emphasize the role of home environment and the influence of family/extended family members and parents (including guardians/substantial care-providers) within the child’s home environment. The direct goal of this initiative is to fund research that will advance knowledge for innovative approaches to the prevention or management of overweight in children less than 6 years of age, with potential for future translation to applications either in the home or linked to a community setting. Research should consider the familial mechanisms of behavior such as the role of families in the initiation, support, and reinforcement of fundamental food and beverage consumption, physical activity practices, and sedentary behaviors. In addition it is of interest to elucidate various underlying behavioral determinants that are crucial to initiate or sustain changes in behaviors that impact energy balance. Research designs may include linkages with other settings (e.g., daycare, pre-school, or other community venues) or other care providers (e.g., health care providers or teachers) but must include infants or children less than age six years as the primary study participant along with parents, and/or other family members residing with the child. The overarching goal is to identify interventions that influence parent and child behaviors that contribute to inappropriate weight gain, and thereby improve subsequent health status in childhood, adolescence, and adulthood for which overweight is a known risk factor.

Program Announcement (PA) Number: PA-10-128

Notice

Applications submitted in response to this Funding Opportunity Announcement (FOA) for Federal assistance must be submitted electronically through Grants.gov (http://www.grants.gov) using the SF424 Research and Related (R&R) forms and the SF424 (R&R) Application Guide.

APPLICATIONS MAY NOT BE SUBMITTED IN PAPER FORMAT.

This FOA must be read in conjunction with the application guidelines included with this announcement in Grants.gov/Apply for Grants (hereafter called Grants.gov/Apply).

A registration process is necessary before submission and applicants are highly encouraged to start the process at least four (4) weeks prior to the grant submission date.

Key Dates

Release/Posted Date: March 9, 2010
Opening Date: May 16, 2010 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): May 16, 2010
NOTE: On-time submission requires that applications be successfully submitted to Grants.gov no later than 5:00 p.m. local time (of the applicant institution/organization).
Application Due Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm
AIDS Application Due Date(s): Not applicable.
Peer Review Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm#reviewandaward
Council Review Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm#reviewandaward
Earliest Anticipated Start Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm#reviewandaward
Expiration Date: May 8, 2013

Home and Family Based Approaches for the Prevention or Management of Overweight or Obesity in Early Childhood (R01)

National Institute of Health
http://grants.nih.gov/grants/guide/pa-files/PA-10-127.html

This Funding Opportunity Announcement (FOA) issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Heart, Lung and Blood Institute (NHLBI), the Office of Behavioral and Social Sciences Research (OBSSR) and the Office of Disease Prevention (ODP), National Institutes of Health, invites exploratory pilot/feasibility study and small clinical trial (R21) applications from institutions/organizations that propose to test novel home or family based interventions for the prevention or management of overweight in infancy and early childhood. Tested interventions can use behavioral (including dietary and physical activity), environmental, or other relevant approaches. Applications should focus on infants and young children (to age six years) and emphasize the role of home environment and the influence of family/extended family members and parents (including guardians/substantial care-providers) within the child’s home environment. The direct goal of this initiative is to fund research that will advance knowledge for innovative approaches to the prevention or management of overweight in children less than 6 years of age, with potential for future research clinical trial applications either in the home or linked to a community setting. Research should consider the role of families in the initiation, support, and reinforcement of fundamental food and beverage consumption, physical activity practices, and sedentary behaviors. In addition it is of interest to elucidate various underlying behavioral determinants that are crucial to initiate or sustain changes in behaviors that impact energy balance. Research designs may include linkages with other settings (e.g., daycare, pre-school, or other community venues) or other care providers (e.g., health care providers or teachers) but must include infants or children less than age six years as the primary study participant along with parents, and/or other family members residing with the child. The overarching goal is to identify interventions that influence parent and child behaviors that contribute to inappropriate weight gain, and thereby improve subsequent health status in childhood, adolescence, and adulthood for which overweight is a known risk factor.

APPLICATIONS MAY NOT BE SUBMITTED IN PAPER FORMAT.

This FOA must be read in conjunction with the application guidelines included with this announcement in Grants.gov/Apply for Grants (hereafter called Grants.gov/Apply).

A registration process is necessary before submission and applicants are highly encouraged to start the process at least four (4) weeks prior to the grant submission date.

Key Dates

Opening Date: May 16, 2010 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): May 16, 2010
NOTE: On-time submission requires that applications be successfully submitted to Grants.gov no later than 5:00 p.m. local time (of the applicant institution/organization).
Application Due Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm
AIDS Application Due Date(s): Not applicable.
Peer Review Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm#reviewandaward
Council Review Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm#reviewandaward
Earliest Anticipated Start Date(s): Standard dates apply, please see http://grants1.nih.gov/grants/funding/submissionschedule.htm#reviewandaward
Expiration Date: May 8, 2013

Hilda and Preston Davis Foundation

Postdoctoral Fellowship in Eating Disorders Research

The Hilda and Preston Davis Foundation is pleased to support its Postdoctoral Fellowship Program in Eating Disorders Research. By attracting young scientists to the field, each fellowship may lead to a lifetime career contribution to understanding the biological causes of eating disorders. The long term goal of the program is to accelerate medical research discoveries that will lead to improved therapies for anorexia nervosa and bulimia nervosa.

Research areas of interest include but are not limited to neural pathways of feeding behavior in animal models; molecular genetic analysis of relevant neural circuit assembly and function; testing of new chemical compounds that might be used in animal models as experimental treatments; and brain imaging technologies that identify neurochemical pathways in patients with these disorders. Clinical psychotherapeutic studies, medication trials and obesity research are currently outside the scope of this Program.

Awards:

Up to five three-year fellowships ranging from $43,000 - $63,000 per year, inclusive of a $3,000 expense allowance will be awarded to fellows who have completed no more than three years of postdoctoral research training as of the funding start date. The awards will support postdoctoral fellows working in nonprofit academic or research institutions in the United States.

Eligability Criteria and Application Information: Visit www.tmfgrants.org/davis

Application Deadline: Thursday, January 14, 2010 (12:00 PM ET)

For more information: Please direct questions to Jeanne Brown, Program Officer at jbrown@hria.org.

Request for Proposals: Outcomes with REALIZE™ Adjustable Gastric Band-C (also referred to as SAGB-VC)

The ETHICON ENDO-SURGERY Bariatrics Grant Program is pleased to announce an opportunity for investigators experienced with the REALIZE™ Adjustable Gastric Band-C or SAGB-VC to analyze and publish their retrospective outcomes data from patients implanted for at least one year (12 months). In addition to weight loss, complication data and site band adjustment practices, ETHICON ENDO-SURGERY encourages applicants to include other study parameters such as:

Effects of weight loss with REALIZE™ Band-C on concomitant disease states (Type 2 Diabetes Mellitus, sleep apnea, CVD, infertility, NASH, etc.)
Effects of weight loss with REALIZE™ Band-C on patient reported quality of life and/or body image
Role of pre-surgery patient attributes (patient selection) on weight loss with REALIZE™ Band-C (e.g., blood chemistry, demographics, BMI range, etc.)
Factors prompting patients to opt for surgical intervention with REALIZE™ Band-C for weight loss
Maintenance of weight loss with REALIZE™ Band-C more than 1-yr post implantation and the effect of other factors (e.g., exercise programs, support groups, dietary programs) on maintenance

Only applications for clinical study proposals for collection and analysis of retrospective data will be reviewed. ETHICON ENDO-SURGERY is not currently seeking applications for prospective study proposals and such proposals will not be considered under this program.

Applicants are asked to submit:

An Application at ETHICON ENDO-SURGERY Investigator-initiated Study (IIS) grant portal
A Protocol Summary
Line item budget
A timeline including all key milestones for study preparation/execution and manuscript submission
A Full CV for Principal Investigator (PI)
Patient follow-up rate at one-year
A brief description of your bariatric program, including patient volume, procedural site of care, pre-surgical preparation process and post-surgical support program(s) offered/required

Award:

Funding of up to $75,000 will be provided for up to 6 proposals. All accepted proposals are expected to result in publication of findings in a peer-reviewed journal. There are no indirect costs provided with this grant program. Budget may include (but is not limited to) costs for data acquisition, compilation, analysis, and interpretation, manuscript development, and presentation.

Eligability:

All other factors equal, preference will be given to applications for which a manuscript can be submitted for publication by March 2010.
All proposals will be reviewed and approved based upon the scientific quality of the study and its alignment with ETHICON ENDO-SURGERY’s ethical and commercial interests.
All funded trials are required to obtain IRB approval to ensure appropriate consent and/or handling of personal health information of retrospective patient data, and to register with the National Clinical Trial Registry (as a retrospective study enrollment will be noted as completed when the study is registered).

Application Instructions:

All questions and proposals should be submitted electronically to the Ethicon Endo-Surgery Office of IIS Administration at IIS@its.jnj.com or applications may be made via the web at http://www.ethiconendo.com/dtcf/pages/IIS.htm?pgn=9 .

Deadline for Submission: November 20, 2009
Recipients of Grant will be notified: December 15, 2009
Final manuscript suitable for submission to peer-reviewed journal is due September 1, 2010
Funding will be issued based upon a fully executed milestone-based agreement

Klarman Family Foundation Grants Program in Eating Disorders Research

The Klarman Family Foundation is interested in providing strategic investment in translational research that will accelerate progress in developing effective treatments for anorexia nervosa, bulimia nervosa and binge eating disorder. The Program's short-term goal is to support the most outstanding science and expand the pool of scientists whose research explores the basic biology of eating disorders. The long-term goal is to improve the lives of patients suffering from these conditions.

Examples of funding areas include but are not limited to molecular genetic analysis of relevant neural circuit assembly and function; animal models created by genetically altering neural circuits; testing of new chemical entities that might be used in animal models as exploratory treatments; and brain imaging approaches that identify neurochemical pathways in patients with these disorders. Investigators conducting research in the neuro-circuitry of fear conditioning or reward behavior may also apply but must justify the relevance of their research projects to the basic biology of eating disorders. Clinical psychotherapeutic studies, medication trials and research in the medical complications of these disorders are outside the scope of this Program.

Application Deadline: December 8, 2009

Application Guildelines and Instructions: www.tmfgrants.org/klarman

Award Categories: 2-year projects of $400,00 USD. 1-year pilot studies of up to $150,00 USD

Eligibility: Applicants must hold a faculty appointment at a nonprofit acadedmic, medical or research institution in the United States, Canada or Israel.

Questions: glockwood@hria.org or 617-279-2240, X702

GSK Consumer Healthcare’s alli® Clinical Research Grant Program

RFA: Clinical Pilot Studies in Obesity

The alli® Clinical Research Grant Program is pleased to announce an opportunity for investigators interested in performing a clinical pilot study (up to 1 year) using orlistat 60 mg. Possible study questions to be explored include, but are not limited to the

1) effects of orlistat on disease states (Type 2 Diabetes Mellitus, NASH, CVD)
2) effects of orlistat on feeding behavior (binge eating disorders, eating patterns)
3) effects of orlistat on gene expression
4) role of orlistat as a weight loss tool
Studies may be blinded controlled, open label or in vitro. Orlistat 60 mg cannot be used in any animal studies. Any application for animal studies will not be reviewed.

Applicants are asked to submit:

• An Application Form
• A Full Research Protocol
• A Full CV for Principal Investigator (PI)
• An IRB Approval Letter (Necessary for commencement of study)

Awards of $25,000 (including supplies) will be awarded to up of 2 proposals. There are no indirects costs provided with this grant program. Clinical packaging, labeling and storage of orlistat 60 mg and statistical support will be considered on an individual basis.

All proposals will be reviewed and approved based upon the scientific quality of the study and its alignment with GSK’s ethical and commercial interests. In some cases, the PI may be required to open an Investigator IND.
All funded trials are required to register with the National Clinical Trial Registry.
Data obtained from these studies may be used to support claims for orlistat 60 mg products.

All questions and proposals should be submitted electronically to:
Dr. Evan Berk at evan.s.berk@gsk.com

The Deadline for Submission is May 15, 2009
Recipients of Grant will be notified by June 30, 2009
Funding/Supplies to be available by September 30, 2009
Study to be completed by September 30, 2010
Final Report to GSK is due January 1, 2011

In addition to this research grant program, GSK Consumer Healthcare continues to offer a clinical supplies only program. There is no deadline to apply for this option and applications are evaluated on a rolling decision process.

Other Funding Sources

Johns Hopkins General Internal Medicine Postdoctoral Fellowship Program: The Johns Hopkins University Division of General Internal Medicine is seeking applicants for its postdoctoral fellowship program. A diverse faculty base in the Division allows for a broad range of research options in obesity research. For additional details, please visit: http://www.hopkinsmedicine.org/gim/fellowship/interest_area.html

The Nutritional Science Research Group, in the Division of Cancer Prevention at the National Cancer Institute, has issued a new funding opportunity announcement titled "Exploratory/Developmental Clinical Research Grants in Obesity (R21)." Information about this Program Announcement (PA) can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06-256.html. The goal of this PA is to encourage exploratory/developmental clinical studies that will accelerate the development of effective interventions for prevention or treatment of overweight or obesity in either adults or children. Please direct any questions about scientific/research issues that relate to obesity and cancer to Dr. Sharon Ross by phone at 301-594-7547 or by e-mail at rosssha@mail.nih.gov.

Executive Office: 8630 Fenton Street, Suite 814, Silver Spring, MD 20910 | Tel: (301) 563-6526 | Fax: (301) 563-6595